About one-third of bones is organic matter, and the other two-thirds are primarily composed of mineral.
Bones are made of connective tissue reinforced with calcium and specialized bone cells. Most bones also contain bone marrow, where blood cells are made. Bone has both organic and inorganic components. Its organic components include the cells and osteoid , the organic part of the matrix.
The organic component of the bone matrix includes the collagen and ground substance whereas the inorganic component is the inorganic bone salts, mainly the hydroxyapatite. The collagen and ground substance form approximately 25% of the bone mass.
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