Acetlycholine ,neurotransmitter is released at the sympathetic chain ganglia. Primary neurotransmitter of sympathetic ganglion neuron is nor-epinephrine except the sweat gland which receives sympathetic cholinergic.
Epinephrine released by the adrenal medulla acts as neurohormone that amplifies sympathetic responses. That neurotransmitter nor-epinephrine , both are stimulatory. The neurons system of CNS that is involved when stressors is encountered is the SNS stimulation of the adrenal glands.
Dopamine is used as medication . It acts on sympathetic nervous system. Dopamine leads to increased heart rate and blood pressure . It cannot cross the blood brain barrier, it does not directly affect the nervous system.
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