For both actin and microtubule polymerization, nucleotide hydrolysis is important for controlling the growth of a microtubule.
Polymerization dynamics enable microtubules to adopt rapidly changing spatial arrangements and, in some cases, perform mechanical tasks according to cellular needs. Microtubules harness the energy of GTP hydrolysis to drive a unique polymerization mechanism called dynamic instability.
Microtubules are one of the main components of the cytoskeleton and are rigid hollow rods approximately 25 nm in diameter. microtubules. are made up of dimers of α- and β-tubulin which polymerize to form microtubules, which are composed of 13 protofilaments assembled around a hollow core.
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