Respuesta :
33-year-old client with thalassemia whose partner is 55 years of age and who have a son with Duchenne muscular dystrophy will have the highest risk for carrying a child with genetic abnormality.
What is Duchenne muscular dystrophy?
A hereditary condition known as Duchenne muscular dystrophy (DMD) is characterized by advancing muscle weakening and degeneration as a result of changes to a protein called dystrophin, which aids in maintaining healthy muscle cells. One of the four diseases referred to as dystrophinopathies is DMD. The other three disorders in this category are DMD-associated dilated cardiomyopathy (heart disease) with little to no clinical skeletal, or voluntary, muscle dysfunction, Becker muscular dystrophy (BMD, a moderate variant of DMD), and an intermediate clinical presentation between DMD and BMD.
Early infancy is when DMD symptoms first appear, generally between the ages of 2 and 3. Although it seldom happens, the condition mostly affects boys.
The frequency of DMD is around 6 per 100,000 people in Europe and North America.
To know more about genetic abnormality:
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