contestada

Exposure of zebrafish nuclei to cytosol isolated from eggs at metaphase of mitosis resulted in phosphorylation of NEP55 and L68 proteins by cyclin-dependent kinase 2. NEP55 is a protein of the inner nuclear membrane, and L68 is a protein of the nuclear lamina. What is the most likely role of phosphorylation of these proteins in the process of mitosis? (A) They enable the attachment of the spindle microtubules to kinetochore regions of the centromere. (B) They are involved in chromosome condensation. (C) They are involved in the disassembly of the nuclear envelope. (D) They assist in the migration of centrosomes to opposite sides of the nucleus.

Respuesta :

Exposure of zebrafish nuclei to cytosol isolated from eggs at metaphase of mitosis resulted in phosphorylation of NEP55 and L68 proteins by cyclin-dependent kinase 2. NEP55 is a protein of the inner nuclear membrane, and L68 is a protein of the nuclear lamina.  The most likely role of phosphorylation of these proteins in the process of mitosis because they are involved in the disassembly of the nuclear envelope.

So, the correct option is (C).

  • The zebrafish, as a vertebrate, possesses the same primary organs and tissues as humans. They have similar muscles, blood, kidneys, and eyeballs to humans. Zebrafish have an extraordinary ability to rebuild cardiac muscle.
  • Transfer of blastula cell nuclei into non-enucleated unfertilized zebrafish eggs results in the development of nuclear transplants.
  • At the start of mitosis, the cyclin-dependent kinase causes the nuclear envelope to disassemble. INM protein phosphorylation impairs their interaction with chromatin. The disintegration of the nuclear envelope is required for sister chromatid segregation.
  • The breakdown of the zebrafish nuclear envelope necessitates consecutive phosphorylation events by PKC, followed by Cdc2 kinase.

To learn more about zebrafish.

brainly.com/question/28217035

#SPJ4

Otras preguntas