The ratio of the two phosphate species [HPO4^2] / [H2PO4] is 5.75
The bicarbonate ions neutralize the hydronium ions and produce carbonic acid and water if an acidic substance enters the bloodstream.
The blood's buffering mechanism already includes carbonic acid. As a result, hydronium ions are eliminated, keeping the blood's pH from becoming acidic.
Plasma proteins, phosphate, as well as bicarbonate and carbonic acid buffers, all operate as part of the blood plasma's buffer systems.
The kidneys contribute to the regulation of acid-base balance by eliminating hydrogen ions and producing bicarbonate, which helps keep the pH of blood plasma within a normal range.
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