The switch of one B cell from producing one class of antibody to another class of antibody that is responsive to the same antigen is due to _______. A. the rearrangement of V region genes in that clone of responsive B cells B. a switch in the kind of antigen-presenting cell that is involved in the immune response C. a patient's reaction to the first kind of antibody made by the plasma cells D. the rearrangement of immunoglobulin heavy-chainC region DNA

Respuesta :

The switch of one B cell from producing one class of antibody to another class of antibody that is responsive to the same antigen is due to the rearrangement of immunoglobulin heavy-chains region DNA

Types of Immunoglobulin

Immunoglobulins were discovered in 1890 by two immunologists, Emil von Behring and Kitasato Shibasaburo, and were first referred to as neutralizing substances.

  • Immunoglobulins are glycoproteins that play a crucial part in the immune system's maintenance.
  • Immunoglobulins, often known as antibodies, are highly specific proteins that are released in large quantities by plasma cells in response to harmful antigens.

Immunoglobulins are Y-shaped globular proteins with a molecular weight of 150kDa and a size of roughly 10nm.

  • All immunoglobulins share four polypeptide subunits
  • Two hefty chains and two light chains that are similar.
  • A disulfide bridge connects the polypeptide chains, forming a Y-shaped structure.

This Y-shaped structure is split into two parts:

The bottom section is referred to as a constant zone & top, the two-arm portion is referred to as a variable region.

Hence, the correct answer is option D

Learn more about immunoglobulins here,

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