The most beneficial medication treatment would be the Alpha-blocker.
The urodynamic term for bladder outlet blockage caused by detrusor muscle contraction and concurrent involuntary urethral sphincter activation is detrusor sphincter dyssynergia (DSD).
If the condition is not monitored and treated properly, some of these neurogenic bladder patients with DSD may be at risk for autonomic dysreflexia, recurrent urinary tract infections, or upper tract compromise. DSD is linked to neurologic conditions like spinal cord injury, multiple sclerosis, and spina bifida.
Additionally, the therapy of isolated detrusor-internal sphincter dyssynergia may benefit from the use of alpha-blockers. Less is known about the effects in patients with detrusor-external sphincter dyssynergia. Controlled investigations on alpha-blockers for the various neurological illness presentations are crucial.
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