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If used during pregnancy, nitrofurantoin was the medicine that could result in the newborn developing eyes that were abnormally tiny.

Viral and fungus infections are not treatable by nitrofurantoin. Only use it if a bacteria is known to be the root of the UTI or is highly suspected of doing so. Nitrofurantoin misuse can raise the danger of toxicity and resistance to antibiotics.

The U.S. Food and Drug Administration (FDA) has approved the use of nitrofurantoin, which has been in use since the 1950s, for the treatment and prevention of bacterial UTIs, including acute cystitis.

Fluoroquinolones and Bactrim (trimethoprim/sulfamethoxazole), which are two antibiotics that are becoming increasingly resistant globally, have raised demand for underutilized medications like nitrofurantoin.

Nitrofurantoin has a good track record for treating bladder infections, but it has a poorer penetration rate for the kidney.

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