Opening all of the sodium channels on an otherwise typical neuron, with all other ion channels closed (which is an admittedly artificial setting), should move its membrane potential to _______. A. -90mV B. 0 mV C. equilibrium potential for sodium D. The membrane potential would not change, only the ion concentrations would change.

Voltage-gated sodium channels create a pore in the cytoplasmic membrane when they are in the open state, allowing sodium ions to enter the cell and depolarizing it to cause the upstroke of the action potential.

The voltage present at any given time across the neuronal membrane is known as the membrane potential (Vm). The membrane's potential at rest is -75 mV.

The constant equilibrium potential attained when only sodium ions may pass across the membrane is known as the sodium equilibrium potential (ENa). ENa is +62 mV in value. However, at depolarized potentials, the majority of sodium channels quickly transition into the "inactivated" state.

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