The DNA microarray is a technology that is used to identify whether a specific person's DNA has mutations in genes like BRCA1 and BRCA2 which cause cancer.
- Therefore, a microarray assesses the quantity of mRNA transcripts in a sample, A genome-wide perspective of gene expression in cancer can be obtained since thousands of gene fragments can be found on an array.
- The idea behind microarrays is that sequences that are complimentary to one another will bind to one another.
- Restrictions endonucleases fragment the unidentified DNA molecules, which are then labeled with fluorescent dyes.
- These are then given a chance to interact with DNA chip probes.
- Chemotherapy has a positive effect on one group while having a negative effect on the other.
- Gene-expression microarrays have shown that the two groups' gene-expression patterns differ.
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