Point mutation, a change in which one base pair in the DNA sequence is changed, occurs within a gene.
By eliminating at least one nucleotide from a gene, a deletion modifies the DNA sequence. Larger deletions can eliminate a whole gene or a number of nearby genes, while smaller deletions just delete one or a few nucleotides from a gene. The function of the affected protein or proteins may change as a result of the deleted DNA.
Short nucleotide changes are referred to as "gene-level mutations" because they affect the particular genes that give instructions for making various functional molecules, including proteins. Variations in these molecules can affect a wide range of an organism's physical traits.
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