Cell types in multicellular organisms differ from each other as they synthesize and accumulate different sets of RNA and protein molecules.
Only a few genes are expressed in cells. These cells have different sets of transcriptional regulators, resulting in different gene expression profiles characteristic of different cell types. All cells can have the same DNA, but not all DNA is actively expressed in all cells. As the cell line matures, certain gene sequences are repressed or "turned off" while others remain active or expressed. Differences between expressed and repressed genes in cells determine their final morphology and function.
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