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What group of periodontal bacteria are often associated with the development of orodigestive cancers such as oral squamous cell, esophageal, pancreatic, and colorectal cancers?.

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Periodontal bacteria such Fusobacterium nucleatum, Treponema denticola, Porphyromonas gingivalis, and Aggregatibacter sp. are frequently linked to the emergence of orodigestive cancers like colorectal, esophageal, pancreatic, and oral squamous cell cancers.

Bacteria from the genera Fusobacterium, Veillonella, Actinomyces, Clostridium, Haemophilus, and Enterobacteriaceae are also associated with epithelial precursor lesions and oral cancer. Numerous studies have also demonstrated the significance of oral infections in the emergence of pancreatic and colorectal cancer. Individual risk factors for the development of oral cancer can include periodontitis. Individuals with impaired periodontal health should be closely watched, especially if they also have severe periodontitis and other risk factors related to their lifestyle. Cancer risks can be reduced in at-risk persons by maintaining their periodontal health.

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