No. Our germline DNA remains constant. While humans may get mutations in particular cells, when DNA is extracted from a blood sample, it is DNA that we have had at birth and have inherited.
... (JERM-line) The germ cell DNA (egg and sperm cells that join to form an embryo). All other cells in the body receive their DNA from the germline.
Changes to your DNA that you inherit from the sperm and egg cells during conception are known as germline mutations. Somatic mutations are modifications to your DNA that take place in cells other than the egg and sperm after conception.
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