Due to fetal hypothyroidism, goiter, and cretinism, anti-thyroid medications are contraindicated during late pregnancy.
Radioiodine therapy is not recommended during pregnancy or breastfeeding. All ant thyroid medications may be given to nursing mothers during the postpartum period, but MMI should be used because PTU may cause hepatotoxicity in either the mother or the child.
The risk of fetal loss and the risk of uncontrolled maternal hyperthyroidism must be balanced before deciding when to perform the thyroidectomy.A high risk of spontaneous abortion is linked to surgery during the first and third trimesters of pregnancy.
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