While NADPH is necessary for the synthesis of several organic compounds, ribose 5 phosphate is required for the synthesis of nucleic acid. The whole oxidation of glucose happens in the cytosol via the pentose phosphate route, which generates NADPH and CO2 but not ATP.
Are biosynthetic reactions dependent on ribose-5-P?
If ribose-5-P is not required for biosynthetic processes but NADPH is.
What results from the reaction of ribulose with glucose-6-phosphate?
In this process, a single molecule of glucose-6-phosphate breaks down into two molecules of NADPH and one molecule of ribulose-5-phosphate in the presence of a water molecule and NADP+.
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