The main characteristic of T cell tolerance is that if the self antigens are from the same tissue or are presented by the same antigen-presenting cell, regulatory cells can suppress autoreactive lymphocytes that identify a variety of distinct self antigens.
The immune system's capacity for self-tolerance is its capacity to see its own antigens as non-threats while appropriately mounting an attack against alien substances. Normal physiological function and general health depend on this equilibrium of immune defense and self-tolerance.
T-helper cells exhibit the surface receptor known as the T cell receptor, which is made up of a polypeptide heterodimer (marked, for example,α/β). T helper cells are able to identify viral peptides in conjunction with class II MHC proteins, which are typically found on an antigen-presenting cell's surface (APC).
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