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During conjugation, if an hfr cell is mated with an f- cell, the f- cell remain f- because the whole Hfr genome could not be transmitted because the cells could not stay in touch for long enough.

What is genome?
Genome is the entirety of an organism's genetic makeup, or DNA. A person's genome is present in nearly every cell in their body. The genome of a person contains all the information needed for growth and development.

Its DNA contains the genes and other elements that control the function of those genes (or RNA in the case of some viruses).

Each and every one of the body's cells, such as the skin cell or the liver cell, carries the following set of instructions: DNA makes up the instructions in our genome. A special chemical code found in DNA directs our growth, development, and health.

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