Respuesta :
Two serious challenges to the building of the Panama Canal were mountainous terrain and tropical diseases such as Yellow Fever i think
Answer:
Yellow fever and malaria killed thousands of men
Explanation:
First, France attempted to build the Panama Canal, but they deserted after more than 21 thousand workers died mostly from landslides and diseases such as yellow fever and malaria. Later, the US attempt to construct the same canal, the same problem emerged: about 6 thousand workers died from yellow fever and malaria, but the US was able to open the canal in 1914.