You need to break up the large square root into smaller square roots
[tex] \sqrt{64x^{10}y^{19}z^{12}} [/tex]
[tex] \sqrt{64} * \sqrt{x^{10}}* \sqrt{y^{19}} * \sqrt{z^{12}} [/tex]
Then we need to simplify the individual radicals
[tex]8*x^{5}*y^{9} \sqrt{y} *z^{6}[/tex]
Now organize these together to get the radical at the end
[tex]8x^{5}y^{9}z^{6} \sqrt{y} [/tex]