When
glucose (or another source of energy) is degraded, it releases protons and
energy. Those protons are stored in the inter-membrane space. When those protons go through
the internal membrane of mithocondria, they make ATPase work, and so ATPase
takes that energy to produce ATP. If anything prevents protons to go through
the internal membrane of mithocondria, then they can’t make ATPase work, and that
energy will be released as heat. The body will “feel” that it needs more ATP,
so it’s like: “oh it seems that I haven’t degraded enough glucose, so let’s
degrade more glucose”. And that will make you loose weight.