What is the main difference between health-related fitness and performance-related fitness? Health-related fitness focuses on cardio activities, while performance-related fitness focuses on strength-training activities. Health-related fitness focuses on strength-training activities, while performance-related fitness focuses on cardio activities. Health-related fitness focuses on improving physical fitness, while performance-related fitness focuses on improving skills. Health-related fitness focuses on improving skills, while performance-related fitness focuses on improving physical fitness.