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If the pH of the body gets too low,below 7.4, acidosis results. Acidosis is serious because many of the chemical reactions that occur in the body are pH-dependent. If the body's pH drops below 6.8 or goes above 7.8, death may occur. Because of this, we have buffers in the blood to protect against large changes in pH. As seen in the above reaction, the human buffer system depends on the fact that

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Diatonic254

Carbon dioxide released from tissue dissolve in the blood plasma to form carbonic acid.It is the best buffer system since it partially dissociates to hydrogen and bicarbonate ions (conjugate base). The amount of H+ ions directly influence the pH. Therefore, the forwards and reverse reactions (catalyzed by carbonic anhydrase enzyme) influence the pH homoeostasis of the body.   
C) all reactants involved are soluble in water.

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