Assess the following statements, and select those that correctly apply to the properties of exotoxins and endotoxins. Check All That Apply Exotoxins typically cause systemic effects, whereas endotoxins precisely target a specific tissue type; e.g., neurological tissue. Exotoxins typically cause systemic effects, whereas endotoxins precisely target a specific tissue type; e.g., neurological tissue. Exotoxins are made of protein that are synthesized and secreted by a living cell, whereas endotoxins are comprised of lipopolysaccharide found in the outer membrane of gram-negative bacteria. Exotoxins are made of protein that are synthesized and secreted by a living cell, whereas endotoxins are comprised of lipopolysaccharide found in the outer membrane of gram-negative bacteria. Endotoxins demonstrate potent toxicity; their lethal dose is low compared to exotoxins, which require a high dose to cause disease manifestations. Endotoxins demonstrate potent toxicity; their lethal dose is low compared to exotoxins, which require a high dose to cause disease manifestations. Hemolysins are examples of endotoxin. They may exhibit β-hemolysis, complete lysis of erythrocytes; or α-hemolysis, partial lysis which manifests as a greenish tinge on blood agar.