If you draw a blood sample from a patient to determine whether he or she has a herpes simplex infection, and the patient displays a large amount of IgG against the virus but low levels of IgM, what do you conclude

Respuesta :

When a patient has high IgG levels against the virus but low IgM levels, it indicates that the patient has had the infection for some time.

IgG plays a crucial role in the humoral immune response and is the predominant immunoglobulin found in blood, lymph fluid, cerebrospinal fluid, and peritoneal fluid. In addition to albumins, enzymes, various globulins, and a host of other proteins, serum IgG makes up roughly 15% of the total protein in healthy persons.

The first antibody the adaptive immune system produces in response to a foreign antigen is IgM. A 180 kDa heterotetramer of monomeric IgM exists.

IgG antibodies don't become detectable until 10–12 days after the infection, although IgM antibodies might be found several days after the initial infection. A positive test result could indicate that you have some immunity to the virus due to prior exposure.

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