A loss of function mutation in the gene encoding UvrA would be associated with an accumulation of unrepaired thymidine dimers.
A pyrimidine deoxy nucleoside, thymidine is often referred to as deoxy thymidine, deoxy ribosyl thymine, or thymine deoxy riboside. The DNA nucleoside T that binds with deoxyadenosine to form double-stranded DNA is deoxythymidine. It is utilized to synchronize the G1/early S phase of the cells in cell biology. Mutation is defined as at a certain gene locus, a deviation from the regular DNA sequence. Although the phrase is frequently associated with negativity, mutation (including polymorphisms) can have a positive, negative, or neutral impact on how cells operate.
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